How do novelists and scientists render visible the invisible? How do they think outside the accumulated meanings of their time? How do they engage the paradoxes of experiment? And how do they confront the risk of disenchantment posed by the process of explanation? This course centers on major literary works ranging from Shelley’s Frankenstein to Flaubert’s Madame Bovary, Woolf’s To the Lighthouse to Brecht’s Galileo. Included as well are scientific texts (e.g., Darwin’s Origin of Species and Einstein’s The Evolution of Physics), engravings (Audubon’s The Birds of America), photographs, schematic figures, and diagrams.